Welcome to the Holstege Lab website

As of January 1st 2016, we have moved to the Princess Maxima Center for Pediatric Oncology. Please check out our new website for our latest research activities. 

We are a molecular biology/biomedical research group with a strong emphasis on functional genomics and systems biology. Our main area of research is investigating how a cell's regulatory machinery works in health and in disease. The long-term goal is to develop Genome Control Maps: wiring-diagram models that describe how regulatory circuitry works at the molecular level across entire genomes. See our mission statement for more details.